Why the study?
Does impedance cardiography reliably measure cardiac output and central blood volume compared to isotope- or thermodilution techniques in healthy subjects and patients with ischaemic heart disease?
Population
37 healthy subjects and 25 unmedicated patients with ischaemic heart disease (total n=62)
Comparison
Impedance cardiography (IC) vs Isotope- or thermodilution techniques
Design
Cross-sectional
Authors
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IC supports tracking CO changes in IHD; leaves open absolute quantification versus dilution methods in practice or trials.
Does impedance cardiography reliably measure cardiac output and central blood volume compared to isotope- or thermodilution techniques in healthy subjects and patients with ischaemic heart disease?
Impedance cardiography is reliable for measuring changes in cardiac output and comparing absolute values between groups, but it overestimates absolute cardiac output and is not recommended for quantifying central blood volume.
Mehlsen et al. (1991) studied this question.
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