January 1, 1978Japanese Circulation Journal-english EditionOpen Access

Experimental Study on the Cause of Ventricular Aberrant Conduction

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Population

Canine heart specimens of both the left bundle branch and right bundle branch systems.

Comparison

Superfusion with oxygenated Tyrode solution and… vs Comparison between four conduction pathways…

Design

Preclinical

Authors

NINobuyuki IwamuraNagoya University

Discussion

Member takes

Implication

May inform mechanisms of RBBB aberrancy; hypothesis-generating in animals, requiring human validation before clinical relevance.

Structured PICO

Population

Canine heart specimens of both the left bundle branch (LBB) and right bundle branch (RBB) systems (n=18 experiments).

Intervention

Superfusion with oxygenated Tyrode solution and simultaneous driving by basic stimuli (cycle length = 750 msec).

Comparator

Comparison between four conduction pathways: main RBB/false tendons, anterior fascicle (AF), posterior fascicle (PF), and septal Purkinje fibers (SEP) of the LBB system.

Outcome

Action potential durations (APD, 80% of repolarization time) and functional refractory period (FRP).surrogate

The shorter action potential duration of septal Purkinje fibers in the left bundle branch system plays an important role in the genesis of the right bundle branch block pattern during aberrant ventricular conduction.

Cite This Study

Nobuyuki Iwamura (1978) studied this question.

synapsesocial.com/papers/6a8a76f7b4e829b19bd484bb https://doi.org/10.1253/jcj.42.491

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Experimental Study on the Cause of Ventricular Aberrant Conduction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Experimental Study on the Cause of Ventricular Aberrant Conduction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider