Why the study?
Do Hemochron, Hemotec, or APTT accurately detect low concentrations of heparin (<1 U/ml) in patients undergoing cardiopulmonary bypass compared to polybrene neutralization?
Population
30 patients undergoing cardiopulmonary bypass
Comparison
Whole blood clotting time using a Hemochron… vs Laboratory measure of heparin concentration by…
Design
Cross-sectional
Authors
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Clinicians should not rely on Hemochron or Hemotec to exclude low residual heparin after CPB; leaves open need for prospective validation of point-of-care alternatives.
Do Hemochron, Hemotec, or APTT accurately detect low concentrations of heparin (<1 U/ml) in patients undergoing cardiopulmonary bypass compared to polybrene neutralization?
Bedside Hemochron and Hemotec analysers do not reliably detect low concentrations of heparin (<1 U/ml) in patients undergoing cardiopulmonary bypass.
Weightman et al. (1996) studied this question.
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