June 22, 2019Journal of Cardiovascular and Thoracic ResearchOpen Access

Reduced myocardial reserve in cirrhotic patients: an evaluation by dobutamine stress speckle tracking and tissue Doppler imaging (TDI) echocardiography

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Why the study?

Despite normal resting systolic function, cirrhotic patients often develop volume overload and heart failure symptoms during stressful situations, prompting evaluation of their myocardial reserve.

Does dobutamine stress echocardiography reveal reduced myocardial reserve in cirrhotic patients compared to normal individuals?

Comparison

Cirrhotic patients vs normal individuals

Authors

MZMahmood ZamirianShiraz University of Medical Sciences FAForough AfsharizadehShiraz University of Medical Sciences AMAlireza MoarefShiraz University of Medical Sciences

Discussion

Member takes

Implication

May indicate reduced myocardial reserve under stress in cirrhosis; leaves open need for larger confirmatory studies before clinical adoption.

Structured PICO

Does dobutamine stress echocardiography reveal reduced myocardial reserve in cirrhotic patients compared to normal individuals?

Population

30 individuals aged 30-50 years, comprising 20 cirrhotic patients (case group) and 10 normal individuals (control group).

Intervention

Dobutamine stress echocardiography with speckle tracking (STE) and tissue Doppler imaging (TDI)

Comparator

Normal individuals undergoing the same dobutamine stress echocardiography protocol

Outcome

Myocardial reserve assessed by ejection fraction (EF), global longitudinal LV strain (GLS), strain rate in the septal basal segment and lateral wall, and E' in the septal basal segment at rest and peak stresssurrogate

Cirrhotic patients with normal resting systolic function exhibit blunted myocardial reserve during dobutamine stress, which may explain their susceptibility to heart failure symptoms during hemodynamic stress.

Cite This Study

Zamirian et al. (2019) studied this question.

synapsesocial.com/papers/6a8a774b238a34ecf4722c9c https://doi.org/10.15171/jcvtr.2019.22

View Full Paper

Ask AI

Bookmark

Implication

May indicate reduced myocardial reserve under stress in cirrhosis; leaves open need for larger confirmatory studies before clinical adoption.

Reduced myocardial reserve in cirrhotic patients: an evaluation by dobutamine stress speckle tracking and tissue Doppler imaging (TDI) echocardiography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Reduced myocardial reserve in cirrhotic patients: an evaluation by dobutamine stress speckle tracking and tissue Doppler imaging (TDI) echocardiography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider