Why the study?
Ultra-endurance sports can cause adverse health effects like exercise-induced muscle damage and exertional rhabdomyolysis, and the role of circulating microRNAs as biomarkers for this damage required investigation.
Do circulating myomiR levels increase and correlate with muscle damage markers in elite athletes after a 24-h ultramarathon run?
Comparison
Biomarker measurements before vs immediately after, 24 h after, and 48 h after a 24-h run
Design
Observational cohort study
Follow-up
48 h after the race
Authors
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Circulating miRNAs may aid EIMD assessment after ultra-endurance events; leaves open clinical utility pending larger validation studies.
Do circulating myomiR levels increase and correlate with muscle damage markers in elite athletes after a 24-h ultramarathon run?
Circulating myomiR levels significantly increase after a 24-h ultramarathon and may serve as useful biomarkers for assessing the degree of exercise-induced muscle damage.
Chalchat et al. (2021) studied this question.
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