What question did this study set out to answer?

To describe an uncommon case of multi-organ peripheral embolism originating from an intracardiac thrombus in a young, previously healthy individual.

April 5, 2022Journal of Clinical MedicineOpen Access

Rare Source of Embolism in a Young Patient: Case Report and Literature Review

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To describe an uncommon case of multi-organ peripheral embolism originating from an intracardiac thrombus in a young, previously healthy individual.
Assessed a 31-year-old male smoker presenting with acute lower-limb ischemia and splenic infarction via computed tomography and coronary angiography.
Performed urgent bilateral lower-extremity embolectomies, followed by coronary artery bypass grafting, surgical resection of left ventricular masses, and hematological evaluation.
Coronary angiography revealed total occlusion of the left anterior descending artery with collateral vessel formation and regional ventricular wall motion abnormalities.
Pathological examination confirmed extirpated left ventricular masses as thrombi, and hematological testing diagnosed homozygous thrombophilia, establishing the need for lifelong anticoagulation.

Structured PICO

Population

31-year-old patient, smoker, with no previous medical history, presenting with acute limb ischemia and infarction of the spleen due to peripheral embolism from left ventricular thrombi.

Intervention

Acute bilateral embolectomy of the iliac, femoral, and popliteal arteries, followed by coronary bypass surgery, extirpation of left ventricular masses, and lifelong anticoagulation therapy.

Highlights a rare presentation of peripheral embolism originating from a left ventricular thrombus in a young patient with silent LAD occlusion and homozygous thrombophilia.

Discussion

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Implication

Alerts clinicians to embolic risk from LV thrombi in young MI patients; leaves open prospective assessment of screening and therapy.

Cite This Study

Vachalcová et al. (2022) studied this question.

synapsesocial.com/papers/6a8a81f9b4e829b19bd48896 https://doi.org/10.3390/jcm11072038

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Rare Source of Embolism in a Young Patient: Case Report and Literature Review

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Rare Source of Embolism in a Young Patient: Case Report and Literature Review

Key Points

Structured PICO

Discussion

Implication

Cite This Study

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