Adiposity, Body Composition and Ventricular–Arterial Stiffness in the Elderly: The Atherosclerosis Risk in Communities Study
Why the study?
Is increased adiposity associated with increased ventricular-arterial stiffness in elderly community-dwelling individuals?
Population
5,520 community-based, elderly, biracial participants from the Atherosclerosis Risk in Communities Study
Design
Cohort
Authors
Discussion
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Member takes
Implication
Body fat percentage may better index adiposity-related stiffness than BMI; hypothesis-generating for HF mechanisms and needs prospective confirmation.
Structured PICO
Is increased adiposity associated with increased ventricular-arterial stiffness in elderly community-dwelling individuals?
P
Population
5,520 community-based, elderly, biracial participants from the Atherosclerosis Risk in Communities (ARIC) Study
I
Intervention
Adiposity measures (body mass index, waist circumference, and body fat percentage)
O
Outcome
Ventricular-arterial stiffness measures including carotid-femoral pulse wave velocity (cfPWV), arterial elastance index (EaI), left ventricular (LV) end-systolic elastance index (EesI) and LV end-diastolic elastance index (EedI)surrogate
Increased adiposity, particularly body fat percentage, is independently associated with increased ventricular-arterial stiffness in the elderly, suggesting a potential mechanism for obesity-related heart failure.
Cite This Study
Fernandes-Silva et al. (2018) studied this question.