Population
L-type Ca channels from porcine cardiac sarcolemma incorporated into planar lipid bilayers
Design
Preclinical
Authors
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Biophysical mapping of dual Ca2+ sites in L-type channels; extends pore models but leaves open human translation.
The study provides direct experimental evidence for at least two symmetrically located high-affinity Ca2+ binding sites within the pore of cardiac L-type calcium channels.
Rosenberg et al. (1991) studied this question.
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