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August 1, 1989Journal of the American Geriatrics Society

Hypertension in the Aging Patient Implications for the Selection of Drug Therapy

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Why the study?

Does antihypertensive therapy, specifically ACE inhibitors and calcium channel blockers, improve outcomes and quality of life in elderly patients with hypertension?

Population

Elderly patients with hypertension (predominantly systolic hypertension)

Design

Review

Authors

MBMichael BursztynHGHaralambos Gavras

Discussion

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Overview

Supports hypertension control in elderly; leaves open randomized trials confirming ACE inhibitors and calcium channel blockers as first-line.

Structured PICO

Does antihypertensive therapy, specifically ACE inhibitors and calcium channel blockers, improve outcomes and quality of life in elderly patients with hypertension?

P
Population
Elderly patients with hypertension (predominantly systolic hypertension)
I
Intervention
Antihypertensive therapy, specifically angiotensin-converting enzyme (ACE) inhibitors and calcium channel blockers
O
Outcome
Cardiovascular and cerebrovascular events

ACE inhibitors and calcium channel blockers are recommended as first-line antihypertensive therapy in elderly patients due to their efficacy in reducing cardiovascular events and favorable side effect profiles.

Cite This Study

Bursztyn et al. (1989) studied this question.

synapsesocial.com/papers/6a8a8fefaf6b08ee8d7240b8https://doi.org/10.1111/j.1532-5415.1989.tb02246.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Calcium Antagonists in the Treatment of Arterial Hypertension in the Elderly2008 · 4 citations
  2. 2Captopril in the Treatment of the Elderly Hypertensive Patient1985 · 86 citations
  3. 3A Single-Blind, Randomized, Cross-over Study of Angiotensin-Converting Enzyme Inhibitor and Triamterene and Hydrochlorothiazide in the Treatment of Mild to Moderate Hypertension in the Elderly1987 · 24 citations
  4. 4Diltiazem, nifedipine, and their combination in patients with stable angina pectoris: effects on angina, exercise tolerance, and the ambulatory electrocardiographic ST segment.1988 · 104 citations
  5. 5The efficacy and safety of long-term antihypertensive therapy with nifedipine.1986 · 6 citations