Why the study?
Does exercise training improve exercise capacity safely in a patient awaiting heart transplantation on intravenous milrinone?
Does exercise training improve exercise capacity safely in a patient awaiting heart transplantation on intravenous milrinone?
Exercise training appears safe and may improve exercise capacity in a patient awaiting heart transplantation on continuous intravenous milrinone.
Hypothesis-generating for supervised exercise in advanced HF on inotropes awaiting transplant; larger prospective trials needed before practice change.
The safety and efficacy of exercise training in patients with congestive heart failure (CHF) is well established; however, the impact that exercise has on the subgroup of CHF patients awaiting heart transplant while on intravenous positive inotropic support remains largely unreported. This case study describes the safety and efficacy of exercise training in a patient awaiting heart transplant while on intravenous milrinone. Over a 1.2-year period, 246 exercise sessions were conducted with a total of 180.15 hours of aerobic exercise. During that time, the patient experienced only one hypotensive episode during exercise and had no other adverse events. The patient demonstrated a 38% increase in aerobic exercise time and a 34% increase in sustainable exercise workload. Research is needed to demonstrate the positive impact of exercise training on this subgroup of CHF patients.
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Arena et al. (2000) studied this question.
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