Why the study?
Does diabetes or atherosclerosis alter the constrictor response of retinal vessels to oxygen inhalation compared to controls?
Population
112 subjects, comprising 47 control subjects, 50 diabetic patients, and 15 persons with atherosclerosis…
Comparison
Inhalation of oxygen vs Control subjects
Design
Cross-sectional
Authors
Loading...
Diabetes impairs retinal vascular reactivity independently of retinopathy; hypothesis-generating for microvascular biomarkers and requires prospective validation.
Does diabetes or atherosclerosis alter the constrictor response of retinal vessels to oxygen inhalation compared to controls?
Diabetes mellitus, even without retinopathy or hypertension, significantly impairs retinal vascular reactivity, whereas uncomplicated atherosclerosis does not.
Hickam et al. (1960) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: