Why the study?
Is vascular reactivity reduced in children with type I diabetes mellitus compared to healthy children, and how does it relate to diabetic control?
Population
62 children (28 with type I diabetes mellitus and 34 healthy controls)
Comparison
Assessment of vascular reactivity in response to… vs Healthy children
Design
Case-control
Authors
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Impaired vascular reactivity in diabetic children may signal early endothelial dysfunction; leaves open causal links to glycemic control and need for prospective validation.
Is vascular reactivity reduced in children with type I diabetes mellitus compared to healthy children, and how does it relate to diabetic control?
Children with type I diabetes exhibit reduced vascular reactivity compared to healthy controls, which correlates with parameters of diabetic control but cannot be fully explained by carbohydrate control alone.
Ewald et al. (1985) studied this question.
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