Key result
Diabetes, hypertension, and hyperglycaemia significantly impaired retinal vascular oxygen reactivity compared to normotensive non-diabetic controls (17.17-30.49% vs 41.16%, P<0.05).
Why the study?
Does hypertension and hyperglycemia impair retinal vascular oxygen reactivity in diabetic subjects?
Population
Normotensive and hypertensive diabetic subjects, and non-diabetic control subjects.
Comparison
60% oxygen breathing to assess retinal vascular… vs Non-diabetic control subjects, and intra-subject…
Design
Cross-sectional
Authors
Loading...
Impaired retinal vascular oxygen reactivity was associated with diabetes, hypertension, and hyperglycemia; hypothesis-generating for prospective studies on autoregulation and outcomes.
Observational
Does hypertension and hyperglycemia impair retinal vascular oxygen reactivity in diabetic subjects?
p-value: p=<0.05
Diabetes impairs retinal vascular autoregulation, which is further worsened by clinically relevant hyperglycemia and hypertension.
Patel et al. (1994) conducted an observational in Diabetes Mellitus. Diabetes, hypertension, and hyperglycaemia vs. Normotensive non-diabetic subjects was evaluated on Retinal vascular autoregulation to 60% oxygen breathing (oxygen reactivity) (p=<0.05). Diabetes, hypertension, and hyperglycaemia significantly impaired retinal vascular oxygen reactivity compared to normotensive non-diabetic controls (17.17-30.49% vs 41.16%, P<0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: