Why the study?
Metastatic adrenocortical carcinoma has limited treatment options and a poor prognosis, and the survival benefit of adrenal surgery in patients with synchronous metastatic disease has not been well explored.
Does adrenal surgery improve overall survival in patients with synchronous metastatic adrenocortical carcinoma?
Population
202 patients with synchronous metastatic ACC from the SEER database (2010-2016)
Comparison
Adrenal surgery vs nonsurgical management
Design
Population-based retrospective cohort study
Authors
Loading...
Primary tumor resection was associated with improved survival in metastatic ACC; leaves open optimal patient selection for prospective trials.
Does adrenal surgery improve overall survival in patients with synchronous metastatic adrenocortical carcinoma?
Adrenal surgery is associated with improved overall survival in patients with synchronous metastatic adrenocortical carcinoma, except for those with liver metastases.
Wu et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: