Population
Skeletal myosin light chains (dissociated by DTNB), troponin-C (TnC), and Whiting parvalbumin
Comparison
High salt (0.6 M NaCl) or monovalent cations vs Ca2+ or Mg2+
Design
Preclinical
Authors
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May influence muscle protein function in high-salt states; leaves open translation to cardiac physiology or clinical outcomes.
High salt concentrations induce conformational changes in skeletal muscle calcium-binding proteins that mimic the effects of calcium binding.
Mrakovcic et al. (1979) studied this question.
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