Population
Vertebrate skeletal myosin
Design
Preclinical
Authors
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pH effects on skeletal myosin assembly remain in vitro only; leaves open relevance to cardiac thick filaments in vivo.
The study demonstrates that the self-assembly of vertebrate skeletal myosin in sodium pyrophosphate is highly pH-dependent, shifting from monomers to minifilaments as pH decreases from 8.5 to 7.0.
Reisler et al. (1986) studied this question.
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