Population
Synthetic thick filaments of skeletal myosin generated at pH 8.2
Design
Preclinical
Authors
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In vitro myosin kinetics remain preclinical; leaves open extension to cardiac thick filament function in vivo.
This biophysical study reveals complex, phase-dependent thermodynamic and kinetic properties in the assembly of synthetic skeletal myosin thick filaments.
Julien S. Davis (1985) studied this question.
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