Why the study?
Angiosarcoma is rare and difficult to diagnose, and Kasabach-Merritt syndrome is rarely reported in adults with angiosarcoma.
Highlights a rare presentation of Kasabach-Merritt syndrome in an adult with metastatic angiosarcoma.
May prompt biopsy in atypical consumptive coagulopathy; leaves open optimal management for adult angiosarcoma-associated KMS.
Angiosarcoma is an incredibly rare type of malignancy, accounting for only 1%-2% of all soft-tissue sarcomas globally. It is clinically, pathologically and radiologically difficult to diagnose angiosarcoma owing to its varied presentation with little or no well-defined imaging findings.Kasabach-Merritt syndrome is also a lesser-heard entity which carries extremely poor prognosis. It is primarily seen in infants with vascular malformations and in kaposiform haemangioendothelioma. It is a condition of consumptive coagulopathy and only few of the cases have been reported so far in the adults with a background of angiosarcoma.This report presents the case of a male in his 70s who was diagnosed with metastatic angiosarcoma and experienced a complicated disease course due to Kasabach-Merritt syndrome.
No takes yet. Share an insight, caveat, or question.
Dhabhar et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: