Key result
Hepatic angiosarcoma can present with Kasabach-Merritt syndrome driven by trapped platelets and coagulation factor consumption.
Why the study?
The mechanism governing the deregulated coagulopathy in hepatic angiosarcoma, fulfilling criteria of disseminated intravascular coagulation, has been poorly understood and KMS associated with angiosarcoma has not been well recognized.
Case Report (n=1)
This case report provides the first histological evidence of Kasabach-Merritt syndrome associated with hepatic angiosarcoma.
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Histological link to DIC in hepatic angiosarcoma; hypothesis-generating and requires validation before clinical adoption.
Wadhwa et al. (2017) conducted a case report in Hepatic angiosarcoma (n=1). Hepatic angiosarcoma was evaluated. Hepatic angiosarcoma can present with Kasabach-Merritt syndrome, supported by histological evidence of coagulation factor consumption and trapped platelets within the tumor.
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