Why the study?
Does long-term prophylactic aspirin reduce the risk of myocardial infarction in asymptomatic and healthy men?
Population
Asymptomatic and healthy male physicians
Comparison
Aspirin for prophylactic purposes on a long-term… vs Control cohort
Design
Review, randomized (in the reviewed studies)
Follow-up
average of 5 to 6 years
Authors
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Conflicting trial results leave aspirin's role in primary MI prevention for healthy men unresolved; further studies needed to clarify net benefit.
Does long-term prophylactic aspirin reduce the risk of myocardial infarction in asymptomatic and healthy men?
This review highlights conflicting results from two large trials on the efficacy of prophylactic aspirin for preventing MI in healthy men.
Saran Jonas (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: