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August 23, 2026Retina

The impact of renal function on pars plana vitrectomy for proliferative diabetic retinopathy and analysis of prognosis

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Authors

YWYalin WangXKXianxian KongJWJing Wang

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Overview

Retrospective study observes visual recovery after vitrectomy in proliferative diabetic retinopathy, indicating systemic health drives outcomes rather than renal function alone.

Key Points

  • To determine the impact of renal impairment on surgical outcomes and identify independent predictors of visual prognosis following pars plana vitrectomy for proliferative diabetic retinopathy.
  • Retrospective study of 110 patients (110 eyes) undergoing pars plana vitrectomy, divided by chronic kidney disease staging into impaired renal function (52 eyes) and normal renal function (58 eyes) groups.
  • Tracked clinical parameters, surgical interventions, and best-corrected visual acuity preoperatively and across a 1-year postoperative follow-up.
  • Performed multivariable regression analysis to identify independent risk factors influencing postoperative visual acuity recovery.
  • The impaired renal function group exhibited significantly longer diabetes duration, lower serum albumin, lower hemoglobin, and greater need for intraoperative silicone oil tamponade (all P < 0.05).
  • Final visual improvement rate at 12 months did not differ significantly between the normal and impaired renal function groups (P = 0.156), with comparable rates of postoperative complications.
  • Multivariable analysis identified longer diabetes duration and lower serum albumin as independent risk factors for poorer visual prognosis, while renal function itself was not an independent predictor.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a8aadc57677a341144461ffhttps://doi.org/10.1097/iae.0000000000004972
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Personalized Management of Patients With Proliferative Diabetic Vitreo-Retinopathy2024 · 1 citations
  2. 2Vitrectomy in eyes with diabetic retinopathy and light perception vision: A comprehensive outcome analysis.2025
  3. 3Pars Plana Vitrectomy Combined with Anti-VEGF Injections as an Approach to Treat Proliferative Diabetic Retinopathy2025 · 3 citations
  4. 4Predictive Factors of Functional Prognosis in Patients with Rhegmatogenous Retinal Detachment Treated by Pars Plana Vitrectomy—A Retrospective Study2026
  5. 5Surgical Outcomes Of Pars Plana Vitrectomy In Aded And Prognostic Factors For Poor Visual Outcomes2025