Key result
PMBV achieves a ~91% success rate, significantly expanding mitral valve area.
Why the study?
The short-term clinical, echocardiographic, and hemodynamic consequences of percutaneous mitral balloon valvuloplasty in rheumatic mitral stenosis were analyzed to assess its safety and efficacy.
Does percutaneous mitral balloon valvuloplasty improve short-term clinical, echocardiographic, and hemodynamic outcomes in patients with rheumatic mitral stenosis?
Cohort (n=53)
No
Does percutaneous mitral balloon valvuloplasty improve short-term clinical, echocardiographic, and hemodynamic outcomes in patients with rheumatic mitral stenosis?
Answers are grounded in this paper and cite their sources.
May support PMBV for short-term hemodynamic gain in rheumatic MS; leaves open durability and comparative efficacy in randomized trials.
Objective: We sought to analyze short-term clinical, echocardiographic, and hemodynamic consequences of percutaneous mitral balloon valvuloplasty (PMBV) in the treatment of rheumatic mitral stenosis (MS) in our clinic. Methods:We retrospectively reviewed 53 patients (49 females, 5 males; mean age 38±11 years) who underwent PMBV for moderate or severe MS between January 2010 and October 2014.Procedural success was defined as the reaching a mitral valve area (MVA) >1.5 cm 2 and absence of grade 3 mitral regurgitation.Results: We were able to perform PMBV in 48 of 53 patients (91%) and all the procedures that were completed were successful.PMBV couldn't be performed in 3 patients due to inability to pass the mitral valve, 1 patient due to membranous obstructive vena cava and 1 patient due inability to perform septostomi.Two patients who underwent successful PMBV became symptomatic after an average of 14 months follow-up and mitral valve replacement was performed due to moderate-to-severe MS.Patients were followed for an average of 13 ± 8 months and atrial fibrillation development or embolic complications were not observed.Conclusion: Percutaneous mitral balloon valvuloplasty procedure is a safe and effective treatment approach with high success and low complication rates in experienced centers.
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Abdülkadir Yıldız (2014) conducted a cohort in Rheumatic mitral stenosis (n=53). Percutaneous mitral balloon valvuloplasty (PMBV) vs. Pre-procedural baseline was evaluated on Procedural success (mitral valve area >1.5 cm2 and absence of grade 3 mitral regurgitation). Percutaneous mitral balloon valvuloplasty achieved a 91% procedural success rate, significantly increasing the mean mitral valve area from 1.1 cm2 to 1.9 cm2 (p<0.001).
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