Radiation therapy can cause severe silent ischemia presenting as reversible ischemic cardiomyopathy, which can be successfully treated with bypass surgery.
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May support bypass in radiation-induced cardiomyopathy; hypothesis-generating and should not yet change practice.
A 55-year-old woman presented with profound congestive heart failure 23 years following mediastinal radiation. Ejection fraction (EF) was 35%. Symptoms markedly improved and EF increased to > 55% following saphenous vein bypass for > or = 80% ostial left main stenosis. Radiation therapy, a known risk factor for coronary atherosclerosis, may present with reversible severe silent ischemia.
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Aronow et al. (1996) studied this question.
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