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January 12, 2010ORL

Paraganglioma of the Larynx

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Key result

Paragangliomas of the larynx are typically benign, rarely functional tumors that present at an average age of 47, are 3 times more common in women, and mostly arise from the supraglottic larynx (82%).

Population

Patients with paragangliomas of the larynx (2 new cases and literature review)

Design

Review

Authors

LBLeon BarnesNovartis (Switzerland)

Discussion

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Implication

Urges histologic confirmation to distinguish from atypical carcinoids; leaves open prospective validation of benign behavior.

Study Design

Type

Case Report

Structured PICO

P
Population
Two cases of laryngeal paraganglioma and a literature review showing the tumor typically occurs in patients averaging 47 years of age and is 3 times more common in women.
O
Outcome
Clinicopathologic profile of the tumor

Paragangliomas of the larynx are typically benign tumors that most commonly occur in the supraglottic larynx of middle-aged women, and alleged malignant cases are often misdiagnosed atypical carcinoids.

Cite This Study

Leon Barnes (2010) conducted a case report in Paraganglioma of the larynx. Paragangliomas of the larynx are typically benign, rarely functional tumors that present at an average age of 47, are 3 times more common in women, and mostly arise from the supraglottic larynx (82%).

synapsesocial.com/papers/6a8acbc890fae8fd47e94a07https://doi.org/10.1159/000276221
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nonfunctional paraganglioma of the larynx: Clinical and pathological considerations1981 · 34 citations
  2. 2Laryngeal Paraganglioma: An Updated Critical Review2004 · 83 citations
  3. 3Paraganglioma in supraglottic area: A rare case report2013
  4. 4Laryngeal Paraganglioma1980 · 3 citations
  5. 5Identification, Classification, Treatment, and Prognosis of Laryngeal Paraganglioma1994 · 92 citations