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July 1, 1994Annals of Otology Rhinology & Laryngology

Identification, Classification, Treatment, and Prognosis of Laryngeal Paraganglioma

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Population

62 cases of laryngeal paraganglioma, predominantly female, median age 44 years.

Design

Case_series

Authors

AFAlfio FerlitoUniversity of PaduaLBLeon BarnesNovartis (Switzerland)BWBruce M. WenigMoffitt Cancer Center

Discussion

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Implication

Supports avoiding malignant classification of laryngeal paragangliomas; leaves open validation in larger cohorts.

Structured PICO

P
Population
62 cases of laryngeal paraganglioma (54 from literature, 8 unpublished from the Armed Forces Institute of Pathology), predominantly female (41:14), median age 44 years.
I
Intervention
Surgical resection
O
Outcome
Clinicopathologic features, diagnosis, and prognosis

Laryngeal paragangliomas are overwhelmingly benign neoplasms that are often misdiagnosed as malignant neuroendocrine carcinomas, leading to inappropriate classification and perceived aggressive behavior.

Limitations

  • Clinical information lacking on 7 literature cases

Cite This Study

Ferlito et al. (1994) studied this question.

synapsesocial.com/papers/6a895785451a22fc7efb8ca0https://doi.org/10.1177/000348949410300705
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A clinico-pathological classification of laryngeal paraganglioma1992 · 20 citations
  2. 2Paraganglioma of the Inferior Laryngeal Paraganglia: A Case Report1992 · 23 citations
  3. 3Glomus jugulare tumors revisited: A ten‐year statistical follow‐up of 231 cases1985 · 126 citations