Key result
The SCN5A mutation S1103Y exists in a white family and is associated with a considerable risk of syncope, ventricular arrhythmia, ventricular fibrillation, and sudden death.
Why the study?
Is the SCN5A mutation S1103Y associated with cardiac arrhythmias and sudden death in the white population?
Case Report
Is the SCN5A mutation S1103Y associated with cardiac arrhythmias and sudden death in the white population?
The SCN5A S1103Y mutation, previously reported mainly in African Americans, is also present in the white population and confers a significant risk of ventricular arrhythmias and sudden death.
No takes yet. Share an insight, caveat, or question.
Should not yet change practice in white patients; extends S1103Y arrhythmia risk beyond African Americans but remains hypothesis-generating.
Chen et al. (2002) conducted a case report in Cardiac arrhythmias and sudden death. SCN5A mutation S1103Y was evaluated on Syncope, ventricular arrhythmia, ventricular fibrillation, and sudden death. The SCN5A mutation S1103Y exists in a white family and is associated with a considerable risk of syncope, ventricular arrhythmia, ventricular fibrillation, and sudden death.
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