Key result
Specific antiviral therapy and multiple other treatments failed to prevent a fatal outcome in a case of neonatal echovirus 7 infection.
This case report highlights the potential for treatment failure in neonatal echovirus 7 infection despite antiviral therapy and IVIG.
Neonatal echovirus 7 may prove fatal despite antivirals and IVIG; leaves open need for effective therapies and systematic study.
We describe a case of fatal neonatal enteroviral infection caused by echovirus 7. Multiple treatments, including specific antiviral therapy, were attempted and failed. Studies of the viral isolate, maternal plasma, intravenous immunoglobulin preparations and pleconaril were performed to identify potential causes for treatment failure.
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Rentz et al. (2006) studied this question. Specific antiviral therapy and multiple other treatments failed to prevent a fatal outcome in a case of neonatal echovirus 7 infection.
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