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October 1, 2024CARDIOVASCULAR THERAPY AND PREVENTIONOpen Access

SCORE2 cardiovascular risk stratification of an urban adult population sample and evaluation of its effectiveness based on 5-year follow-up

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Why the study?

The effectiveness of cardiovascular risk stratification using the SCORE2 scale needed evaluation in a Tomsk adult population sample based on 5-year follow-up.

Does the SCORE2 scale accurately predict cardiovascular events in an urban adult population aged 40-64 years?

Population

971 people aged 40 to 64 years in Tomsk

Comparison

Cardiovascular risk stratification using clinical data, carotid ultrasound, and SCORE2

Design

Population-based cohort study

Follow-up

5-year follow-up

Key result

The SCORE2 scale classified 98% of relatively healthy individuals as high or very high risk, but their incidence of cardiovascular events was only 1% over 5 years (p=0.004).

Authors

АЗА. Р. ЗаироваАРА. Н. РогозаEOE. Oschepkova

Discussion

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Overview

Clinical-anamnestic plus carotid ultrasound stratification captures most events; leaves open SCORE2 utility without local recalibration in Russian adults.

Study Design

Type

Cohort (n=971)

Structured PICO

Does the SCORE2 scale accurately predict cardiovascular events in an urban adult population aged 40-64 years?

P
Population
971 adults aged 40 to 64 years from a Tomsk population sample, followed for 5 years to evaluate cardiovascular risk stratification methods.
E
Exposure
Cardiovascular risk stratification using the SCORE2 scale and clinical/anamnestic data (with and without carotid ultrasound).
O
Outcome
Incidence of cardiovascular events (composite of cardiovascular death, non-fatal myocardial infarction, or stroke) over 5-year follow-up.composite

Main Result

p-value: p=0.004

The SCORE2 scale significantly overestimated cardiovascular risk in a relatively healthy Russian cohort, classifying 98% as high or very high risk despite a 5-year event rate of only 1%.

Cite This Study

Заирова et al. (2024) conducted a cohort in Cardiovascular risk (n=971). SCORE2 cardiovascular risk stratification was evaluated on Cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or stroke) (p=0.004). The SCORE2 scale classified 98% of relatively healthy individuals as high or very high risk, but their incidence of cardiovascular events was only 1% over 5 years (p=0.004).

synapsesocial.com/papers/6a8af67b60c8c47a9ee3b413https://doi.org/10.15829/1728-8800-2025-4184
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Validation of SCORE2 on a sample from the Russian population and adaptation for the very high cardiovascular disease risk region2024 · 22 citations
  2. 2The prevalence of carotid atherosclerosis in spontaneous populations in Tomsk2014 · 10 citations
  3. 3Correctness of cardiovascular risk assessment in daily clinical practice2021 · 12 citations
  4. 4Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. Ten years later2021 · 133 citations
  5. 5ESSE-RF study: epidemiology and public health promotion2021 · 28 citations