Key result
In patients on chronic hemodialysis, coronary artery calcification (Agatston score) was inversely correlated with plasma adiponectin levels (r=-0.44, p=0.01) and positively correlated with the calcium-phosphate product.
Cross-Sectional (n=32)
No
Effect estimate: r=-0.44
p-value: p=0.01
Low plasma adiponectin levels, alongside abnormal calcium and phosphate metabolism, are significantly associated with increased coronary artery calcification in hemodialysis patients.
May link adiponectin and mineral metabolism to coronary calcification in hemodialysis; hypothesis-generating and should not yet change practice.
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Watanabe et al. (2006) conducted a cross-sectional in Hemodialysis (n=32). Plasma adiponectin level was evaluated on Correlation between Agatston score and plasma adiponectin level (r=-0.44, p=0.01). In patients on chronic hemodialysis, coronary artery calcification (Agatston score) was inversely correlated with plasma adiponectin levels (r=-0.44, p=0.01) and positively correlated with the calcium-phosphate product.
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