Key result
New high throughput electrophysiological techniques based on arrays of planar silicon chips are predicted to revolutionize ion channel drug discovery compared to conventional patch clamping.
New high throughput electrophysiological techniques, such as planar silicon chip arrays, are emerging to improve ion channel drug discovery compared to conventional patch clamping.
No takes yet. Share an insight, caveat, or question.
May accelerate ion channel screening; leaves open whether planar chips outperform patch clamping in practice.
Willumsen et al. (2003) conducted a review in Channelopathies. High throughput electrophysiological techniques vs. Conventional patch clamp was evaluated. New high throughput electrophysiological techniques based on arrays of planar silicon chips are predicted to revolutionize ion channel drug discovery compared to conventional patch clamping.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: