Why the study?
Does high-altitude residency or chronic mountain sickness alter the ventilatory response to CO2 compared to sea-level residency?
Does high-altitude residency or chronic mountain sickness alter the ventilatory response to CO2 compared to sea-level residency?
High-altitude natives and patients with chronic mountain sickness demonstrate higher central chemoreflex sensitivity to CO2 in euoxia and longer central time constants compared to sea-level natives.
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High-altitude residency and CMS were associated with heightened central CO2 chemoreflex; leaves open mechanisms, causality, and clinical relevance.
Fatemian et al. (2003) studied this question.
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