Why the study?
Does an 8-h exposure to hypoxia increase peripheral or central chemosensitivity to CO2 in healthy volunteers?
Population
10 healthy volunteers
Comparison
8-h exposure to isocapnic hypoxia (PET = 55… vs 8-h exposure to air-breathing control
Design
Other
Follow-up
8 hours
Authors
Loading...
No immediate clinical implications for hypoxic patients; leaves open relevance of chemosensitivity changes to disease states or interventions.
Does an 8-h exposure to hypoxia increase peripheral or central chemosensitivity to CO2 in healthy volunteers?
Sustained hypoxia induces a significant increase in chemosensitivity to CO2 within the peripheral chemoreflex in healthy humans.
Fatemian et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: