Key result
Sepsis was associated with significantly lower variability of both heart rate and EEG relative alpha power, and a reduction of their coupled oscillations compared with controls.
Why the study?
Does sepsis alter heart rate and EEG variability and their coupling compared to controls?
Population
52 patients with sepsis (30 comatose, 22 noncomatose) and 11 control subjects
Comparison
30-minute EEG and electrocardiogram recording vs 11 control subjects
Design
Cohort
Authors
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Suggests neurocardiac uncoupling may serve as a noninvasive marker for sepsis.
Observational (n=63)
Does sepsis alter heart rate and EEG variability and their coupling compared to controls?
Sepsis is associated with reduced heart rate and EEG variability and their uncoupling, which correlates with the severity of encephalopathy.
Admiraal et al. (2017) conducted an observational in Sepsis (n=63). Sepsis vs. Control subjects was evaluated on Heart rate variability, EEG variability, and their coupled oscillations. Sepsis was associated with significantly lower variability of both heart rate and EEG relative alpha power, and a reduction of their coupled oscillations compared with controls.
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