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June 1, 2000Critical Care Medicine

Linear and nonlinear analysis of hemodynamic signals during sepsis and septic shock

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Population

30 pediatric patients with sepsis or septic shock in a pediatric intensive care unit in a tertiary care…

Design

Case_series

Authors

DTDaniel ToweillUniversity of WashingtonKSKaren SonnenthalDoernbecher Children's HospitalBKBrent KimberlyUnited States Department of Veterans Affairs

Discussion

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Implication

May aid differentiation of pediatric sepsis from shock; single-case data leaves open prospective validation before clinical adoption.

Structured PICO

P
Population
30 pediatric patients with sepsis or septic shock in a pediatric intensive care unit in a tertiary care children's hospital.
C
Comparator
Sepsis vs. septic shock vs. recovery states
O
Outcome
Neuroautonomic modulation of heart rate and blood pressure using power spectral analysis and detrended fluctuation analysissurrogate

Uncoupling of the autonomic and cardiovascular systems occurs during sepsis, and hemodynamic signal analysis may help differentiate between sepsis, septic shock, and recovery states in pediatric patients.

Cite This Study

Toweill et al. (2000) studied this question.

synapsesocial.com/papers/6a7c2372169fe1af7cc2a770https://doi.org/10.1097/00003246-200006000-00063
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