February 1, 1994Journal of Spinal Disorders
Increase in Creatine Kinase MB Isoenzyme Levels after Spinal Surgery
Why the study?
Does spinal surgery cause elevations in CK-MB levels in the absence of myocardial injury?
Population
17 adults undergoing 20 consecutive spinal surgical procedures
Design
Cohort
Follow-up
postoperatively
Authors
Discussion
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Member takes
Implication
CK-MB elevations after spinal surgery may reflect muscle trauma, not MI; Level 3 data leaves open validation of cardiac-specific markers in this setting.
Structured PICO
Does spinal surgery cause elevations in CK-MB levels in the absence of myocardial injury?
P
Population
17 adults undergoing 20 consecutive spinal surgical procedures
I
Intervention
Spinal surgery
O
Outcome
Frequency of postoperative elevations of CK-MB and their clinical correlatessurrogate
CK-MB elevations frequently occur after spinal surgery due to skeletal muscle injury, indicating that these enzyme levels should not be used in isolation to diagnose myocardial infarction in this population.
Cite This Study
Lenke et al. (1994) studied this question.