Why the study?
Does pindolol combined with classical antihypertensives improve blood pressure lowering compared to pindolol monotherapy in hypertensive patients?
Does pindolol combined with classical antihypertensives improve blood pressure lowering compared to pindolol monotherapy in hypertensive patients?
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Pindolol is an effective and safe treatment for hypertension, with more consistent blood pressure lowering when combined with a diuretic.
Two groups of twenty-five hypertensive patients each were treated with a beta-adrenergic blocking agent (pindolol), either alone or in combination with classical anthihypertensives. In the group under monotherapy a significant lowering of the blood pressure was observed. The effect was, however, not so consistent as in the group under combined therapy. The trial shows the efficacy and safety of pindolol in the treatment of hypertension mainly if applied in combination with a diuretic.
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Jaroonvesma et al. (1978) studied this question.
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