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June 1, 1979CirculationOpen Access

Temporal response of left ventricular performance to mitral valve surgery.

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Why the study?

Does mitral valve replacement surgery improve left ventricular performance and hypertrophy in patients with mitral regurgitation or stenosis?

Population

33 patients (16 with mitral regurgitation and 17 with mitral stenosis)

Comparison

Mitral valve replacement surgery vs Pre-surgery baseline

Design

Cohort

Follow-up

average of 15 months

Authors

GSGerhard SchülerGoethe University FrankfurtKPKirk L. PetersonHeart Failure & TransplantAJA. JohnsonUniversity of Washington

Discussion

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Overview

May indicate reverse remodeling after mitral valve surgery in MR; leaves open effects on performance, hypertrophy, or stenosis.

Structured PICO

Does mitral valve replacement surgery improve left ventricular performance and hypertrophy in patients with mitral regurgitation or stenosis?

P
Population
33 patients (16 with mitral regurgitation and 17 with mitral stenosis)
I
Intervention
Mitral valve replacement surgery
C
Comparator
Pre-surgery baseline
O
Outcome
Temporal changes in left ventricular performance and hypertrophy (end-diastolic dimension, end-systolic dimension, and left ventricular muscle cross-sectional area) measured by echocardiographysurrogate

Mitral valve replacement surgery significantly reduces left ventricular end-diastolic dimension in patients with mitral regurgitation.

Cite This Study

Schüler et al. (1979) studied this question.

synapsesocial.com/papers/6a8bab953fd21775a533ae94https://doi.org/10.1161/01.cir.59.6.1218
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left ventricular function before and following aortic valve replacement.1977 · 205 citations
  2. 2Mechanics of Left Ventricular Contraction in Chronic Severe Mitral Regurgitation1973 · 158 citations
  3. 3Clinical and Hemodynamic Studies in Patients with Homograft Mitral Valve Replacement1971 · 27 citations
  4. 4Myocardial mechanics in aortic and mitral valvular regurgitation: the concept of instantaneous impedance as a determinant of the performance of the intact heart1968 · 194 citations
  5. 5Mechanical and Myocardial Factors in Rheumatic Heart Disease with Mitral Stenosis1955 · 147 citations