Why the study?
Is enterovirus-specific RNA more frequently detected in the serum of patients with chronic fatigue compared to acutely ill or healthy individuals?
Population
88 patients with chronic fatigue, 82 acutely ill individuals with symptoms consistent with presumed…
Comparison
Nested polymerase chain reaction assay targeting… vs Acutely ill individuals with presumed…
Design
Case-control
Authors
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Does not support routine testing or treatment changes; leaves open causal role of enteroviral persistence in chronic fatigue.
Is enterovirus-specific RNA more frequently detected in the serum of patients with chronic fatigue compared to acutely ill or healthy individuals?
Enteroviral RNA is frequently detected in the serum of patients with chronic fatigue, suggesting a potential persistent enterovirus infection in a subset of these patients.
Clements et al. (1995) studied this question.
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