The Predictive Value of H2FPEF Score for Contrast Induced Nephropathy in NSTEMI Patients Undergoing Emergency PCI

Background and Aim: Contrast-induced nephropathy (CIN) is acute kidney damage that occurs after recent radiographic contrast media exposure.The aim of our study was to evaluate the association of H 2 FPEF score with CIN in patients with non-ST-segment elevation myocardial infarction (NSTEMI) undergoing emergency coronary angiography and percutaneous coronary intervention (PCI). Materials and Methods:This prospective single center study included 600 patients with NSTEMI scheduled for both emergency coronary angiography and PCI.They were classified into 2 groups according to the incidence of CIN: the first group included 89 patients who developed CIN, and the second group included 511 patients without CIN.All studied cases were clinically evaluated.Echocardiographic assessment, coronary angiography and PCI were done.Results: Age, hypertension, diabetes mellitus (DM), presence of heart failure and atrial fibrillation, pulmonary artery systolic pressure and H 2 FPEF were found to be significant predictors of CIN after emergency PCI.Multivariate logistic regression analysis detected age, DM, and H 2 FPEF as the only significant predictors of CIN after emergency PCI.H 2 FPEF score can predict CIN with AUC of 0.575 and P-value of 0.020, at cutoff >1, with 85.39% sensitivity, 50.49% specificity, 16.1% positive predictive value and 89.8% negative predictive value.Conclusion: H 2 FPEF score shows a statistically significant but limited discriminatory ability in predicting CIN.Its utility as a standalone predictor appears limited and requires further validation.