Why the study?
Are high free thyroxine levels associated with QTc prolongation in older adults?
Population
939 adults aged 55 years and older from the Rotterdam Study with an electrocardiogram. Excluded…
Comparison
High free thyroxine (T4) levels (fifth quintile) vs Low free thyroxine (T4) levels (first quintile)
Design
Cohort
Authors
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High free T4 was associated with QTc prolongation in older men; leaves open whether thyroid status informs arrhythmia risk assessment.
Are high free thyroxine levels associated with QTc prolongation in older adults?
High free thyroxine levels are associated with substantial QTc prolongation and increased risk of borderline/prolonged QTc in men, highlighting a potential risk factor for sudden cardiac death.
Noord et al. (2008) studied this question.
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