Why the study?
Does alpha 1-blockade improve maximal forearm vascular conductance in young borderline hypertensives?
Does alpha 1-blockade improve maximal forearm vascular conductance in young borderline hypertensives?
Alpha 1-blockade does not increase maximal forearm vascular conductance in borderline hypertensives, suggesting that structural vascular changes contribute to blood pressure elevation in this group.
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Alpha 1-blockade fails to normalize maximal forearm vascular conductance in borderline hypertensives; supports structural vascular remodeling over functional tone in early hypertension.
Franke et al. (1997) studied this question.
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