Population
Human kidney tissue (three juxtaglomerular apparatuses and one interlobular artery)
Design
Preclinical
Authors
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Renin localization in arterial epithelioid cells leaves open vascular contributions to hypertension; functional human studies needed before clinical relevance.
Provides morphological evidence that granular epithelioid cells synthesize and store renin in both the juxtaglomerular apparatus and larger arteries of the human kidney.
Lindop et al. (1984) studied this question.
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