Key result
Oral administration of enzyme inhibitors in a rat model induced hypertrophy and hyperplasia of juxtaglomerular cells, facilitating the study of renin granules by light and electron microscopy.
This report details methodological procedures for embedding and staining to study renin granules in rat kidneys.
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Rat model enables renin granule microscopy; hypothesis-generating only, with no clinical translation or practice implications.
Tausch et al. (1984) studied this question. Enzyme inhibitors was evaluated on Description of plastic embedding and staining procedures used to study renin granules. Oral administration of enzyme inhibitors in a rat model induced hypertrophy and hyperplasia of juxtaglomerular cells, facilitating the study of renin granules by light and electron microscopy.
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