Why the study?
Does angiotensin II induce angiogenesis via a specific receptor in the chick embryo CAM model?
Population
Chick embryo chorioallantoic membrane (CAM) model
Comparison
Angiotensin II with or without AT receptor… vs Angiotensin II alone or different antagonists
Design
Preclinical
Authors
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Chick CAM data should not change AT1/AT2-targeted therapies; leaves open a distinct non-mammalian angiogenic receptor.
Does angiotensin II induce angiogenesis via a specific receptor in the chick embryo CAM model?
Angiotensin II induces angiogenesis in the chick embryo CAM via a novel receptor distinct from classical mammalian AT1 and AT2 receptors.
Noble et al. (1993) studied this question.
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