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April 17, 2025Reviews in Cardiovascular MedicineOpen Access

Impact of Three-Dimensional Assessment of Maternal Left Ventricular Systolic Function on Pregnancy Outcomes

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Why the study?

Hypertensive disorders in pregnancy are associated with adverse pregnancy outcomes, but the impact of 3D left ventricular systolic function on these outcomes required assessment.

Does three-dimensional assessment of maternal left ventricular systolic function predict adverse pregnancy outcomes in women with hypertensive disorders in pregnancy?

Population

174 women with HDP and 64 controls without previous comorbidities

Comparison

HDP vs controls

Design

Prospective cohort study

Follow-up

Six weeks after delivery

Authors

AIAleksandra IlićSTSnežana TadićDIDjordje Ilić

Discussion

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Member takes

Overview

May support 3D echo risk stratification in HDP; hypothesis-generating and requires prospective validation.

Structured PICO

Does three-dimensional assessment of maternal left ventricular systolic function predict adverse pregnancy outcomes in women with hypertensive disorders in pregnancy?

P
Population
238 primiparous women with singleton pregnancies without previous comorbidities, including 174 with hypertensive disorders in pregnancy (HDP) and 64 controls, median gestational age 34 weeks.
I
Intervention
Three-dimensional (3D) echocardiography assessment of maternal left ventricular systolic function
O
Outcome
Pregnancy outcomes (intrauterine growth restriction (IUGR), preterm delivery, and birth weight)hard clinical

Three-dimensional echocardiographic parameters, specifically LV global area strain and ejection fraction, are strong predictors of adverse pregnancy outcomes such as IUGR and preterm delivery in women with hypertensive disorders in pregnancy.

Cite This Study

Ilić et al. (2025) studied this question.

synapsesocial.com/papers/6a8bd6f89ac394ad33cabdb5https://doi.org/10.31083/rcm27639
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic Effect of Left Atrial Function by Three‐Dimensional Speckle‐Tracking Echocardiography on Adverse Pregnancy Outcomes in Patients With Hypertensive Disorders of Pregnancy: A Preliminary Study2025
  2. 2Structural and functional changes in maternal left ventricle during pregnancy: a three-dimensional speckle-tracking echocardiography study2015 · 103 citations
  3. 3Left Ventricular Function in Gestational Hypertension: Serial Echocardiographic Study2009 · 26 citations
  4. 4The importance of global area strain in the assessment of the left ventricular systolic function in hypertensive pregnancy2025
  5. 5Echocardiographic Assessment of Cardiovascular Hemodynamic Changes in Hypertensive Disorders of Pregnancy2026