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January 1, 2011Circulation JournalOpen Access

Impact of Gestational Hypertension on Left Ventricular Function and Geometric Pattern

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Why the study?

Does gestational hypertension impair left ventricular function and alter geometric patterns in previously normotensive young women?

Population

199 pregnant women, including 106 with gestational hypertension and 93 normotensive pregnant women.

Comparison

Gestational hypertension (exposure) vs Normotensive pregnancy

Design

Cross-sectional

Authors

KCKyoung Im ChoSKSeong-Man KimMSMi‐Seung Shin

Discussion

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Overview

Gestational hypertension may link to subclinical LV impairment in pregnancy; hypothesis-generating and requires longitudinal studies before clinical adoption.

Structured PICO

Does gestational hypertension impair left ventricular function and alter geometric patterns in previously normotensive young women?

P
Population
199 pregnant women, including 106 with gestational hypertension (mean age 32.3 ± 4.2 years) and 93 normotensive pregnant women (mean age 30.2 ± 4.4 years).
I
Intervention
Gestational hypertension (exposure)
C
Comparator
Normotensive pregnancy
O
Outcome
Left ventricular function and geometric pattern assessed by transthoracic echocardiography (including 2-dimensional strain, Tei index, LV mass index, and relative wall thickness)surrogate

Gestational hypertension is associated with subclinical left ventricular systolic and diastolic dysfunction, as well as eccentric hypertrophy, compared to normotensive pregnancy.

Limitations

  • The reversibility of these morphological and functional impairments after delivery needs to be clarified

Cite This Study

Cho et al. (2011) studied this question.

synapsesocial.com/papers/6a8648a4cdff5daddc73a54ehttps://doi.org/10.1253/circj.cj-10-0763
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Function in Gestational Hypertension: Serial Echocardiographic Study2009 · 26 citations
  2. 2Maternal Diastolic Dysfunction and Left Ventricular Geometry in Gestational Hypertension2001 · 87 citations
  3. 3Left ventricular geometry in pregnancy-induced hypertension2000 · 25 citations
  4. 4Echocardiographic Assessment of LV Geometric Pattern and Function in Pregnancy-Induced Hypertension2005 · 5 citations
  5. 5Echocardiographic Assessment of Structural and Hemodynamic Changes in Hypertension-Related Pregnancy2016 · 31 citations