Why the study?
Does hypertension during pregnancy alter left ventricular structure and diastolic function compared to normotensive pregnancy?
Population
193 consecutive pregnant women, including normotensive and hypertensive women
Comparison
Hypertension during pregnancy vs Normotensive pregnancy
Design
Cross-sectional
Key result
Hypertensive pregnancy was associated with significantly higher left ventricular mass index (97 vs 84 g/m, p=0.001) and impaired diastolic function compared to normotensive pregnancy.
Authors
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May indicate modified LV remodeling in hypertensive pregnancies; leaves open prognostic implications and need for prospective validation.
Observational (n=193)
No
Does hypertension during pregnancy alter left ventricular structure and diastolic function compared to normotensive pregnancy?
Absolute Event Rate: 97% vs 84%
p-value: p=0.001
Hypertensive pregnancy is associated with significant left ventricular hypertrophy and diastolic dysfunction, with different remodeling patterns observed between gestational and chronic hypertension.
Kim et al. (2016) conducted an observational in Hypertension-Related Pregnancy (n=193). Hypertension during pregnancy vs. Normotensive pregnancy was evaluated on Left ventricular mass index (LVMI) normalized by height (p=0.001). Hypertensive pregnancy was associated with significantly higher left ventricular mass index (97 vs 84 g/m, p=0.001) and impaired diastolic function compared to normotensive pregnancy.