What is the clinical evidence from this study?

Study design: Observational. Population: Pregnancy (n=27). Intervention: Hypertension vs. No hypertension. Primary outcome: Difference in left ventricle diameter during and post pregnancy (p=0.04).

What does this research mean for the field?

Women with hypertensive disorders of pregnancy had a larger left ventricular diameter increase during pregnancy compared to those without hypertension. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To analyze the heart's changes during pregnancy and postpartum in women with and without hypertension.

February 2, 2026European Heart Journal - Cardiovascular Imaging

Pregnancy related cardiac remodeling in patients with and without hypertension -preliminary results

View Full Paper

Ask AI

Bookmark

Key result

Hypertensive pregnancy disorders are linked to a ~3 mm greater increase in LV diameter.

P=0.04
n=27

Why the study?

The study was conducted to analyze morphological and functional cardiac changes during pregnancy and the postpartum period in women with and without hypertension.

Do hypertensive disorders of pregnancy cause greater cardiac morphological and functional remodeling compared to normotensive pregnancies?

Population

27 participants with available follow-up data from 150 recruited pregnant women

Comparison

Women with hypertension vs women without hypertension

Design

Observational cohort study

Follow-up

7.3 (±3.2) months postpartum

Authors

ESEwa SzczerbaMother and Child Foundation EKE Kozyra-PydysMother and Child Foundation AAA AjewskaMother and Child Foundation

Discussion

Member takes

Implication

May heighten surveillance needs in HDP; leaves open prognostic value for postpartum outcomes.

Key Points

To analyze the heart's changes during pregnancy and postpartum in women with and without hypertension.
Recruited 150 pregnant women with hypertensive disorders
Conducted echocardiographic exams during pregnancy and postpartum
Analyzed gestational ultrasound and blood test results
Used Statistica 13 for statistical analysis
Left atrium, left ventricle, and right ventricle sizes were larger during pregnancy than postpartum
Diastolic parameters were similar across pregnancy and postpartum
Left ventricular ejection fraction was higher during pregnancy compared to postpartum
Women with hypertension showed larger left ventricle diameter and different motion velocities in mitral annulus compared to those without hypertension

Study Design

Type

Observational (n=27)

Structured PICO

Do hypertensive disorders of pregnancy cause greater cardiac morphological and functional remodeling compared to normotensive pregnancies?

Population

27 pregnant women (10 with hypertension, 17 without) evaluated by echocardiography at approximately 29 weeks gestation and 7 months postpartum.

Exposure

Hypertensive disorders of pregnancy (pre-existing or gestational)

Comparator

Normotensive pregnancy

Outcome

Morphological and functional changes in the heart measured by echocardiography (including left ventricular size and diastolic function) between pregnancy (around 28.7 weeks) and postpartum (mean 7.3 months)surrogate

Main Result

Absolute Event Rate: 3.1% vs 0.4%

p-value: p=0.04

Hypertensive disorders during pregnancy are associated with more pronounced left ventricular enlargement and greater changes in diastolic function compared to normotensive pregnancies.

Limitations

Preliminary results
Follow-up data available for only 27 participants
Small sample size with follow-up data (n=27)

Cite This Study

Szczerba et al. (2026) conducted an observational in Pregnancy (n=27). Hypertension vs. No hypertension was evaluated on Difference in left ventricle diameter during and post pregnancy (p=0.04). Hypertension during pregnancy was associated with a significantly greater increase in left ventricular diameter compared to normotensive pregnancy (3.1 vs 0.4 mm, p=0.04).

synapsesocial.com/papers/6980ff37c1c9540dea812061 https://doi.org/10.1093/ehjci/jeaf367.124

Topics

Echocardiography

View Full Paper

Ask AI

Bookmark

February 2, 2026European Heart Journal - Cardiovascular Imaging

Pregnancy related cardiac remodeling in patients with and without hypertension -preliminary results

View Full Paper

Ask AI

Bookmark

Key result

Hypertensive pregnancy disorders are linked to a ~3 mm greater increase in LV diameter.

P=0.04
n=27

Why the study?

The study was conducted to analyze morphological and functional cardiac changes during pregnancy and the postpartum period in women with and without hypertension.

Do hypertensive disorders of pregnancy cause greater cardiac morphological and functional remodeling compared to normotensive pregnancies?

Population

27 participants with available follow-up data from 150 recruited pregnant women

Comparison

Women with hypertension vs women without hypertension

Design

Observational cohort study

Follow-up

7.3 (±3.2) months postpartum

Authors

ESEwa SzczerbaMother and Child Foundation EKE Kozyra-PydysMother and Child Foundation AAA AjewskaMother and Child Foundation

Discussion

Member takes

Implication

May heighten surveillance needs in HDP; leaves open prognostic value for postpartum outcomes.

Key Points

To analyze the heart's changes during pregnancy and postpartum in women with and without hypertension.
Recruited 150 pregnant women with hypertensive disorders
Conducted echocardiographic exams during pregnancy and postpartum
Analyzed gestational ultrasound and blood test results
Used Statistica 13 for statistical analysis
Left atrium, left ventricle, and right ventricle sizes were larger during pregnancy than postpartum
Diastolic parameters were similar across pregnancy and postpartum
Left ventricular ejection fraction was higher during pregnancy compared to postpartum
Women with hypertension showed larger left ventricle diameter and different motion velocities in mitral annulus compared to those without hypertension

Study Design

Type

Observational (n=27)

Structured PICO

Do hypertensive disorders of pregnancy cause greater cardiac morphological and functional remodeling compared to normotensive pregnancies?

Population

27 pregnant women (10 with hypertension, 17 without) evaluated by echocardiography at approximately 29 weeks gestation and 7 months postpartum.

Exposure

Hypertensive disorders of pregnancy (pre-existing or gestational)

Comparator

Normotensive pregnancy

Outcome

Main Result

Absolute Event Rate: 3.1% vs 0.4%

p-value: p=0.04

Hypertensive disorders during pregnancy are associated with more pronounced left ventricular enlargement and greater changes in diastolic function compared to normotensive pregnancies.

Limitations

Preliminary results
Follow-up data available for only 27 participants
Small sample size with follow-up data (n=27)

Cite This Study

synapsesocial.com/papers/6980ff37c1c9540dea812061 https://doi.org/10.1093/ehjci/jeaf367.124

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Echocardiography

View Full Paper

Ask AI

Bookmark