Why the study?
Clinical outcomes of Trypanosoma cruzi infection in dogs vary widely, and characterizing cardiac manifestations and evaluating dogs with discordant serology is needed.
Does natural Trypanosoma cruzi infection increase the incidence of cardiac abnormalities in working dogs?
Population
48 government working dogs (39 with successful ambulatory ECG recordings)
Comparison
T. cruzi-infected dogs vs discordant dogs vs matched uninfected dogs
Design
Matched cohort study
Authors
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May warrant ECG monitoring in T. cruzi-positive working dogs; leaves open causality and need for prospective trials.
Does natural Trypanosoma cruzi infection increase the incidence of cardiac abnormalities in working dogs?
Natural T. cruzi infection in working dogs is associated with a significantly higher prevalence of ECG abnormalities and elevated cardiac troponin I compared to uninfected dogs.
Meyers et al. (2020) studied this question.
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