Key result
A naturally-infected dog with Trypanosoma cruzi DTU TcIII exhibited prolonged patent parasitemia, anemia, and cardiac damage indicated by elevated troponin I, NT-ProBNP, and segmental hypokinesia.
Why the study?
Little is known about the progression of Chagas disease in naturally-infected dogs, especially during the acute phase.
Design
Case report
Authors
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Supports cardiac monitoring in TcIII-infected dogs; leaves open strain-specific virulence and requires larger prospective studies.
Case Report (n=1)
This case report documents acute cardiac damage, including elevated biomarkers and echocardiographic abnormalities, in a dog naturally infected with T. cruzi DTU TcIII, highlighting its role as a sentinel for human Chagas disease.
Araújo-Neto et al. (2025) conducted a case report in Chagas disease (Trypanosoma cruzi infection) (n=1). Trypanosoma cruzi infection was evaluated on Clinical, hematological, biochemical, cardiological and parasitological characteristics. A naturally-infected dog with Trypanosoma cruzi DTU TcIII exhibited prolonged patent parasitemia, anemia, and cardiac damage indicated by elevated troponin I, NT-ProBNP, and segmental hypokinesia.
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